Applicability of photoacoustic microscopy to quantitative photoaging evaluation

Hiroki Hattori, Takeshi Namita, Kengo Kondo, Makoto Yamakawa, Tsuyoshi Shiina

研究成果: Conference contribution

抄録

Skin aging caused by ultraviolet light exposure is one of the serious problems from the viewpoint of beauty and healthcare. This is because ultraviolet light can cause age spot, wrinkles, at the worst case, skin cancer and so on. To evaluate skin aging, various modalities are being used, such as histopathological diagnosis, optical imaging (e.g. optical coherence tomography (OCT), second harmonic tomography (SHG)) and ultrasound examination (B-mode imaging). However, they have disadvantages in terms of invasiveness, penetration depth and tissue specificity, respectively. To overcome these defects, photoacoustic imaging (PAI), a novel modality was used in this work. This modality can portray differences of tissue characteristics non-invasively. In this work, human skin tissues in various degrees of photoaging (8 subjects, 2 kind of site each) were measured by using acoustic resolution photoacoustic microscopy (AR-PAM) to verify the feasibility of quantitative skin aging evaluation with PA technique. The effects of photoaging progress on the signal intensity were investigated. The results demonstrated that the PA signal from the dermis increases as photoaging progresses. These analyses demonstrate the feasibility of quantitative skin aging evaluation with a PA imaging system.

本文言語English
ホスト出版物のタイトルPhotons Plus Ultrasound
ホスト出版物のサブタイトルImaging and Sensing 2021
編集者Alexander A. Oraevsky, Lihong V. Wang
出版社SPIE
ISBN(電子版)9781510641198
DOI
出版ステータスPublished - 2021
外部発表はい
イベントPhotons Plus Ultrasound: Imaging and Sensing 2021 - Virtual, Online, United States
継続期間: 2021 3月 62021 3月 11

出版物シリーズ

名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE
11642
ISSN(印刷版)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2021
国/地域United States
CityVirtual, Online
Period21/3/621/3/11

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 原子分子物理学および光学
  • 生体材料
  • 放射線学、核医学およびイメージング

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