Catalytic asymmetric desymmetrization of meso-diamide derivatives through enantioselective N-allylation with a chiral π-allyl Pd catalyst: Improvement and reversal of the enantioselectivity

Osamu Kitagawa, Shinichi Matsuo, Kanako Yotsumoto, Takeo Taguchi

研究成果: Article

18 引用 (Scopus)

抜粋

In the presence of the Trost ligands-Pd catalysts, N-monoallylation of bis(2,4,6-triisopropylbenzne)sulfonylamides derived from meio-1,2-diamines proceeds with good to excellent enantioselectivity (85-96% ee) to give asymmetric desymmetrization products. Under the same conditions, in the reaction with meso-bistolunesulfonylamide derivatives, reversal of the enantioselectivity is observed.

元の言語English
ページ(範囲)2524-2527
ページ数4
ジャーナルJournal of Organic Chemistry
71
発行部数6
DOI
出版物ステータスPublished - 2006 3 17
外部発表Yes

ASJC Scopus subject areas

  • Organic Chemistry

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