Cavitas bio/chemical sensors for internet of things in healthcare

Cavitas bio/chemical sensors attached to body cavities such as contact lens and mouthguard have been developed for future Internet of Things (IoT) medicine. Cavitas is the etymological origin of the word cavity in Latin. «Nonimplantable» and «Nonwearable, » the cavitas bio/chemical sensors in body cavities have many advantages for noninvasive biomonitoring as daily IoT medicine. Hence collectively, cavitas sensors provide biological and chemical information from within the body cavities. As the cavitas sensors, several types of soft contact lens type sensors have been developed for monitoring bio/chemicals (glucose and electrical conductivity) in tear fluid, and transcutaneous gases at eyelid conjunctiva in lacrimal sac. In addition, telemetric IoT mouthguard sensors in oral cavity have been investigated for a real-time measurement of saliva glucose for an estimation of blood sugar level. Here, some challenges regarding the integration of biosensors into monitoring for biological and chemical information for IoT medicine are introduced. The IoT cavitas sensors allow us to improve human quality of life and living standards in the near future.