CHAPTER 5: Rapid and Repeated Measurement of Mite Allergens Using a Surface Acoustic Wave (SAW) Immunosensor

K. Toma, T. Arakawa, K. Mitsubayashi

研究成果: Chapter

抄録

Mite allergens are one of the major causes of allergic disease. Those that are airborne are particularly harmful because people exposed to them can inhale them without noticing, which does not often happen when the allergens are contained in dust. This chapter provides an overview of the technologies relevant to airborne allergen monitoring systems, which will be useful in preventing exposure. Immunosensors are powerful devices with the ability to detect allergens with high selectivity and sensitivity due to the high specificity of antibodies to antigens. However, immunosensors are not always suitable for monitoring because antibodies are possibly denatured and lose their functions during sensor surface regeneration. To overcome this problem, we give an example of an immunosensor that relies on a surface acoustic wave device and a pH resistant surface architecture. The SAW immunosensor allows repeated and rapid measurement of a house dust mite allergen, Dermatophagoides farinae group 1 (Der f 1). Together with other useful state-of-the-art technologies for the monitoring system, such as bioaerosol samplers and sensors with promising characteristics, the current advances in mite allergen sensors are summarized.

本文言語English
ホスト出版物のタイトルCarbon-based Nanomaterials in Analytical Chemistry
編集者Minhaz Uddin Ahmed, Mohammed Zourob, Eiichi Tamiya
出版社Royal Society of Chemistry
ページ86-100
ページ数15
14
ISBN(電子版)9781788011020, 9781788014373
DOI
出版ステータスPublished - 2019
外部発表はい

出版物シリーズ

名前RSC Detection Science
番号14
2019-January
ISSN(印刷版)2052-3068
ISSN(電子版)2052-3076

ASJC Scopus subject areas

  • バイオエンジニアリング
  • 病理学および法医学
  • 化学 (全般)
  • 環境化学
  • 生化学、遺伝学、分子生物学(全般)
  • 汚染
  • 生化学、医学

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