Chiral additive induced self-disproportionation of enantiomers under MPLC conditions: Preparation of enantiomerically pure samples of 1-(aryl)ethylamines from racemates

Mitsuhiro Goto, Kaori Tateishi, Kenki Ebine, Vadim A. Soloshonok, Christian Roussel, Osamu Kitagawa

研究成果: Article

11 引用 (Scopus)

抜粋

Mixtures of enantiomerically pure (S)-N-formyl-1-phenylethyamine and various racemic N-formyl-1-arylethylamine derivatives, when submitted to achiral medium pressure liquid chromatography, afforded elution profiles in which the enantiomers of N-formyl-1-arylethylamines standout as separate peaks and can be isolated. In all of the investigated N-formyl-1-arylethylamine substrates, the virtually enantiomerically pure (S)-enantiomer eluted as a less polar fraction and subsequently, the (R)-enriched enantiomer mixtures were eluted in the more polar fractions.

元の言語English
ページ(範囲)317-321
ページ数5
ジャーナルTetrahedron Asymmetry
27
発行部数7-8
DOI
出版物ステータスPublished - 2016 5 1

    フィンガープリント

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

これを引用