Cloning and characterization of mouse mSox13 cDNA

Susumu Kido, Yoshiki Hiraoka, Motoyuki Ogawa, Yukinao Sakai, Yasunori Yoshimura, Sadakazu Aiso

研究成果査読

20 被引用数 (Scopus)

抄録

A novel SRY-related cDNA, mSox13, was isolated from a λ phage library derived from mouse embryo. The cDNA encodes a protein of 595 amino acids containing the SRY-type high mobility group (HMG) box and a putative leucine zipper motif. A sequence comparison of mSox13 and other type-D SOX proteins shows that the leucine zipper and a neighboring glutamine-rich sequence stretch, which was named Q box, are well conserved among known type-D SOX proteins. The expression of mSox13 is restricted to the kidney and ovary. The electrophoretic mobility shift assay indicates that the recombinant mSox13 protein is capable of binding to the AACAAT sequence.

本文言語English
ページ(範囲)201-206
ページ数6
ジャーナルGene
208
2
DOI
出版ステータスPublished - 1998 2 22
外部発表はい

ASJC Scopus subject areas

  • 遺伝学

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