Daily cocoa intake reduces the susceptibility of low-density lipoprotein to oxidation as demonstrated in healthy human volunteers

Naomi Osakabe, Seigo Baba, Akiko Yasuda, Tamami Iwamoto, Masumi Kamiyama, Toshio Takizawa, Hiroshige Itakura, Kazuo Kondo

研究成果: Article査読

112 被引用数 (Scopus)

抄録

Nine male volunteers were given 36 g of cocoa powder (containing 2610 mg of polyphenols) per day with sugar and 6 volunteers received an equivalent amount of sugar for 2 weeks. Conjugated diene production in LDL induced by 2-2′ azobis(4-methoxy-2, 4-dimethyl-valeronitrile) (V-70) and copper ion were evaluated. The lag time was significantly prolonged at 1 and 2 weeks in V-70 and at 2 weeks in copper ion after cocoa powder consumption. The level of excretion of epicatechin in urine was significantly higher in the cocoa group than that in the control group. In conclusion, the antioxidants in cocoa powder might be absorbed and increase the resistance of human LDL to oxidation.

本文言語English
ページ(範囲)93-99
ページ数7
ジャーナルFree Radical Research
34
1
DOI
出版ステータスPublished - 2001 1月 1
外部発表はい

ASJC Scopus subject areas

  • 生化学

フィンガープリント

「Daily cocoa intake reduces the susceptibility of low-density lipoprotein to oxidation as demonstrated in healthy human volunteers」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル