Determination of polyhexamethylene biguanide hydrochloride using a lactone-rhodamine B-based fluorescence optode

Akane Funaki, Yuta Horikoshi, Teruyuki Kobayashi, Takashi Masadome

研究成果: Article

1 引用 (Scopus)

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A new determination method for polyhexamethylene biguanide hydrochloride (PHMB) using a lactone-rhodamine B (L-RB) based fluorescence optode has been developed. The optode membrane consists of 2-nitrophenyl octyl ether as a plasticizer, L-RB, and poly (vinyl chloride). The optode responds to tetrakis (4-fluorophenyl) borate, sodium salt (NaTPBF) in the µM range. The fluorescence intensity of the L-RB film for PHMB solution containing 20 µM NaTPBF decreased linearly as the concentration of the PHMB solution increased in the concentration range from 0 to 8.0 µM, which shows that PHMB with a concentration range of 0 to 8.0 µM is determined by the L-RB film optode. The concentration of PHMB in the contact lens detergents by the proposed method was in accord with its nominal concentration.

元の言語English
記事番号262
ジャーナルMolecules
25
発行部数2
DOI
出版物ステータスPublished - 2020

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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