Direct observation of immunoreactive sites and antibody molecules by ultrahigh‐resolution scanning electron microscope

Kenjiro Yasuda, Sadakazu Aiso, Takashi Nagatani, Mitsuhiko Yamada

研究成果: Article

2 引用 (Scopus)

抜粋

Using an ultrahigh‐resolution scanning electron microscope (SEM), an attempt was made to directly visualize antibody molecules at antigenic sites in rat pancreas or on silicone plates. Although individual antibody molecules could not be discerned, a fluffy meshwork, probably indicating several molecules, was seen. With further improvements in specimen preparation, the high‐resolution SEM promises to be an important tool in examining individual antibody‐antigen sites without the need of an electron‐dense label such as colloidal gold.

元の言語English
ページ(範囲)155-159
ページ数5
ジャーナルJournal of Electron Microscopy Technique
12
発行部数2
DOI
出版物ステータスPublished - 1989 6
外部発表Yes

ASJC Scopus subject areas

  • Anatomy

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