Electron transfer mediated biosensor with plasma-polymerized film containing redox site

Hitoshi Muguruma, Hideyuki Uehara

研究成果: Article査読

3 被引用数 (Scopus)

抄録

An electron transfer mediated amperometric enzyme biosensor based on a plasma-polymerized thin film of dimethylaminomethylferrocene (DMAMFc) is reported. A nanoscale thin polymer film containing a redox mediator was plasma-deposited directly onto an electrode with physisorbed glucose oxidase (GOD). Since the redox sites were introduced in the vicinity of the reaction centers of GOD, a highly efficient electron transfer system was formed in which almost all the reaction centers of GOD were connected to redox sites of the polymer matrix. The advantages of this strategy were: no need for prior or further chemical modification of the enzyme molecules, and simplicity of design compared with the use of a conventional polymer matrix. Moreover, the fact that the film deposition was performed using a microfabrication-compatible organic plasma promised great potential for high-throughput production of bioelectronic devices.

本文言語English
ページ(範囲)1781-1785
ページ数5
ジャーナルIEICE Transactions on Electronics
E89-C
12
DOI
出版ステータスPublished - 2006 12月

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 電子工学および電気工学

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