Evaluation of shear wave dispersion caused by fibrous structure and tissue viscosity using hepatic fibrosis progression and histological models

Shiori Fujii, Makoto Yamakawa, Masatoshi Kudo, Kengo Kondo, Tsuyoshi Shiina, Takeshi Namita

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

Shear wave elasticity imaging has been utilized for chronic hepatitis diagnosis. The relationship between hepatic fibrosis and elasticity or viscosity has been described recently. Therefore, it is expected that viscosity analysis will improve the accuracy of staging fibrosis, in addition to elasticity measuring. However, fibrous structures affect dispersion slope analysis, so it is necessary to investigate the effect of fibrous structure on dispersion slope analysis. In order to simulate shear wave propagation in liver tissue, we use two types of models representing fibrosis progression. One is created using a potential function, and the other is created from hepatic histological sections. Simulating shear wave propagation in these models without viscosity in order to examine the effect of fibrous structure alone, dispersion analysis was applied to the particle velocity data. We evaluated the dispersion slope and shear wave phase velocity at 200 Hz (c (200 Hz)). In both models, the dispersion slope increased significantly with fibrosis progression. The resulting dispersion slope is about 30% of the dispersion slope in in vivo measurements, indicating that the effect of fibrous structure is large enough for viscosity analysis.

本文言語English
ホスト出版物のタイトル2017 IEEE International Ultrasonics Symposium, IUS 2017
出版社IEEE Computer Society
ISBN(電子版)9781538633830
DOI
出版ステータスPublished - 2017 10月 31
外部発表はい
イベント2017 IEEE International Ultrasonics Symposium, IUS 2017 - Washington, United States
継続期間: 2017 9月 62017 9月 9

出版物シリーズ

名前IEEE International Ultrasonics Symposium, IUS
ISSN(印刷版)1948-5719
ISSN(電子版)1948-5727

Conference

Conference2017 IEEE International Ultrasonics Symposium, IUS 2017
国/地域United States
CityWashington
Period17/9/617/9/9

ASJC Scopus subject areas

  • 音響学および超音波学

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