`Gate effect' of thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate)

Yasuo Yoshimi, Ryo Ohdaira, Chiaki Iiyama, Kiyotaka Sakai

研究成果: Article

81 引用 (Scopus)

抄録

Molecular imprinting is a new technology for the synthesis of polymers with antibody-like specificity, which are potentially useful in sensing or separation devices. Here, we report that a thin layer of molecularly-imprinted copolymer exhibits an increase in its diffusive permeability in the presence of its template. A thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate) of theophylline was observed to form on the surface of electrically conductive indium-tin oxide (ITO) film. Cyclic voltammetry of ferrocyanide was performed using the copolymer-grafted ITO as a working electrode in the presence and absence of the template. The presence of the template was found to enhance the anodic current remarkably, which suggests that the diffusive permeability of the thin layer of the molecularly-imprinted polymer (MIP) is sensitive to the presence of its template molecule. This idea is supported by atomic force microscopy (AFM) in which the surface porosity of the layer of the MIP was observed to increased in the presence of its template. We conclude that the structure and diffusive permeability of a thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate) enables this system to be used as a sensor for a given template.

元の言語English
ページ(範囲)49-53
ページ数5
ジャーナルSensors and Actuators, B: Chemical
73
発行部数1
DOI
出版物ステータスPublished - 2001 2 25

Fingerprint

Polymers
templates
Tin oxides
Indium
acids
Acids
Copolymers
permeability
Theophylline
Antibodies
indium oxides
tin oxides
Cyclic voltammetry
Oxide films
Atomic force microscopy
copolymers
polymers
Porosity
Electrodes
Molecules

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry
  • Electrical and Electronic Engineering

これを引用

`Gate effect' of thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate). / Yoshimi, Yasuo; Ohdaira, Ryo; Iiyama, Chiaki; Sakai, Kiyotaka.

:: Sensors and Actuators, B: Chemical, 巻 73, 番号 1, 25.02.2001, p. 49-53.

研究成果: Article

@article{8eeab381cedb452dadf086a379fd84c7,
title = "`Gate effect' of thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate)",
abstract = "Molecular imprinting is a new technology for the synthesis of polymers with antibody-like specificity, which are potentially useful in sensing or separation devices. Here, we report that a thin layer of molecularly-imprinted copolymer exhibits an increase in its diffusive permeability in the presence of its template. A thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate) of theophylline was observed to form on the surface of electrically conductive indium-tin oxide (ITO) film. Cyclic voltammetry of ferrocyanide was performed using the copolymer-grafted ITO as a working electrode in the presence and absence of the template. The presence of the template was found to enhance the anodic current remarkably, which suggests that the diffusive permeability of the thin layer of the molecularly-imprinted polymer (MIP) is sensitive to the presence of its template molecule. This idea is supported by atomic force microscopy (AFM) in which the surface porosity of the layer of the MIP was observed to increased in the presence of its template. We conclude that the structure and diffusive permeability of a thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate) enables this system to be used as a sensor for a given template.",
author = "Yasuo Yoshimi and Ryo Ohdaira and Chiaki Iiyama and Kiyotaka Sakai",
year = "2001",
month = "2",
day = "25",
doi = "10.1016/S0925-4005(00)00671-7",
language = "English",
volume = "73",
pages = "49--53",
journal = "Sensors and Actuators, B: Chemical",
issn = "0925-4005",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - `Gate effect' of thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate)

AU - Yoshimi, Yasuo

AU - Ohdaira, Ryo

AU - Iiyama, Chiaki

AU - Sakai, Kiyotaka

PY - 2001/2/25

Y1 - 2001/2/25

N2 - Molecular imprinting is a new technology for the synthesis of polymers with antibody-like specificity, which are potentially useful in sensing or separation devices. Here, we report that a thin layer of molecularly-imprinted copolymer exhibits an increase in its diffusive permeability in the presence of its template. A thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate) of theophylline was observed to form on the surface of electrically conductive indium-tin oxide (ITO) film. Cyclic voltammetry of ferrocyanide was performed using the copolymer-grafted ITO as a working electrode in the presence and absence of the template. The presence of the template was found to enhance the anodic current remarkably, which suggests that the diffusive permeability of the thin layer of the molecularly-imprinted polymer (MIP) is sensitive to the presence of its template molecule. This idea is supported by atomic force microscopy (AFM) in which the surface porosity of the layer of the MIP was observed to increased in the presence of its template. We conclude that the structure and diffusive permeability of a thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate) enables this system to be used as a sensor for a given template.

AB - Molecular imprinting is a new technology for the synthesis of polymers with antibody-like specificity, which are potentially useful in sensing or separation devices. Here, we report that a thin layer of molecularly-imprinted copolymer exhibits an increase in its diffusive permeability in the presence of its template. A thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate) of theophylline was observed to form on the surface of electrically conductive indium-tin oxide (ITO) film. Cyclic voltammetry of ferrocyanide was performed using the copolymer-grafted ITO as a working electrode in the presence and absence of the template. The presence of the template was found to enhance the anodic current remarkably, which suggests that the diffusive permeability of the thin layer of the molecularly-imprinted polymer (MIP) is sensitive to the presence of its template molecule. This idea is supported by atomic force microscopy (AFM) in which the surface porosity of the layer of the MIP was observed to increased in the presence of its template. We conclude that the structure and diffusive permeability of a thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate) enables this system to be used as a sensor for a given template.

UR - http://www.scopus.com/inward/record.url?scp=0034818821&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034818821&partnerID=8YFLogxK

U2 - 10.1016/S0925-4005(00)00671-7

DO - 10.1016/S0925-4005(00)00671-7

M3 - Article

AN - SCOPUS:0034818821

VL - 73

SP - 49

EP - 53

JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

SN - 0925-4005

IS - 1

ER -