Genomic structure of the actin-encoding gene of Pneumocystis carinii

Yasushi Miyahira, Yoshiki Hiraoka, Naoki Komatsu, Tsutomu Takeuchi, Sadakazu Aiso

研究成果: Article査読

1 被引用数 (Scopus)

抄録

We have isolated both the genomic and cDNA clones of the actin gene of Pneumocystis carinii and analyzed its genomic structure. The gene consists of eight exons. The introns are uniformly short in size (43-49 nucleotides). Multiple poly(A) sites of the actin mRNA are located in a highly AT-rich portion of the 3′-flanking region of this gene, although the canonical poly(A) signal, AATAAA, is not found in the region. Transcription initiation sites have been determined by the primer extension method. A TATA-box-like sequence is located 39-bp upstream of the 5′-most major initiation site.

本文言語English
ページ(範囲)289-295
ページ数7
ジャーナルParasitology International
46
4
DOI
出版ステータスPublished - 1997 12
外部発表はい

ASJC Scopus subject areas

  • 寄生虫科
  • 感染症

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