抄録
γ-glutamyl transpeptidase (γ-GTP) is a membrane-bound enzyme which is known to play a crucial role in active transport of amino acids across membrane barriers. We prepared a monoclonal antibody recognizing specifically rat γ-GTP and investigated localization of the enzyme in the rat brain by immunohistochemistry with this antibody. The antigen was localized on the ependyma, epithelia of the choroid plexus and microvessels. More precise localization of γ-GTP was examined with immuno-electron microscopy. The antigen was recognized on the microvilli and cilia of the ependymal cells, microvilli of the choroid epithelial cells and luminal membranes of the vascular endothelial cells.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 597-601 |
| ページ数 | 5 |
| ジャーナル | Tissue and Cell |
| 巻 | 30 |
| 発行部数 | 6 |
| DOI | |
| 出版物ステータス | Published - 1998 1 1 |
| 外部発表 | Yes |
ASJC Scopus subject areas
- Developmental Biology
- Cell Biology
これを引用
Immunohistochemical study of localization of γ-glutamyl transpeptidase in the rat brain. / Ogawa, M.; Shiozawa, M.; Hiraoka, Y.; Takeuchi, Y.; Aiso, Sadakazu.
：: Tissue and Cell, 巻 30, 番号 6, 01.01.1998, p. 597-601.研究成果: Article
}
TY - JOUR
T1 - Immunohistochemical study of localization of γ-glutamyl transpeptidase in the rat brain
AU - Ogawa, M.
AU - Shiozawa, M.
AU - Hiraoka, Y.
AU - Takeuchi, Y.
AU - Aiso, Sadakazu
PY - 1998/1/1
Y1 - 1998/1/1
N2 - γ-glutamyl transpeptidase (γ-GTP) is a membrane-bound enzyme which is known to play a crucial role in active transport of amino acids across membrane barriers. We prepared a monoclonal antibody recognizing specifically rat γ-GTP and investigated localization of the enzyme in the rat brain by immunohistochemistry with this antibody. The antigen was localized on the ependyma, epithelia of the choroid plexus and microvessels. More precise localization of γ-GTP was examined with immuno-electron microscopy. The antigen was recognized on the microvilli and cilia of the ependymal cells, microvilli of the choroid epithelial cells and luminal membranes of the vascular endothelial cells.
AB - γ-glutamyl transpeptidase (γ-GTP) is a membrane-bound enzyme which is known to play a crucial role in active transport of amino acids across membrane barriers. We prepared a monoclonal antibody recognizing specifically rat γ-GTP and investigated localization of the enzyme in the rat brain by immunohistochemistry with this antibody. The antigen was localized on the ependyma, epithelia of the choroid plexus and microvessels. More precise localization of γ-GTP was examined with immuno-electron microscopy. The antigen was recognized on the microvilli and cilia of the ependymal cells, microvilli of the choroid epithelial cells and luminal membranes of the vascular endothelial cells.
KW - Choroid plexus
KW - Ependymal cell
KW - Immunohistochemistry
KW - Vascular endothelial cell
KW - γ-glutamyl transpeptidase
UR - http://www.scopus.com/inward/record.url?scp=0032443869&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032443869&partnerID=8YFLogxK
U2 - 10.1016/S0040-8166(98)80078-5
DO - 10.1016/S0040-8166(98)80078-5
M3 - Article
C2 - 10036785
AN - SCOPUS:0032443869
VL - 30
SP - 597
EP - 601
JO - Tissue and Cell
JF - Tissue and Cell
SN - 0040-8166
IS - 6
ER -