Immunohistochemical study of localization of γ-glutamyl transpeptidase in the rat brain

M. Ogawa, M. Shiozawa, Y. Hiraoka, Y. Takeuchi, S. Aiso

研究成果: Article査読

13 被引用数 (Scopus)

抄録

γ-glutamyl transpeptidase (γ-GTP) is a membrane-bound enzyme which is known to play a crucial role in active transport of amino acids across membrane barriers. We prepared a monoclonal antibody recognizing specifically rat γ-GTP and investigated localization of the enzyme in the rat brain by immunohistochemistry with this antibody. The antigen was localized on the ependyma, epithelia of the choroid plexus and microvessels. More precise localization of γ-GTP was examined with immuno-electron microscopy. The antigen was recognized on the microvilli and cilia of the ependymal cells, microvilli of the choroid epithelial cells and luminal membranes of the vascular endothelial cells.

本文言語English
ページ(範囲)597-601
ページ数5
ジャーナルTissue and Cell
30
6
DOI
出版ステータスPublished - 1998
外部発表はい

ASJC Scopus subject areas

  • 発生生物学
  • 細胞生物学

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