Immunohistochemical study of localization of γ-glutamyl transpeptidase in the rat brain

M. Ogawa, M. Shiozawa, Y. Hiraoka, Y. Takeuchi, Sadakazu Aiso

研究成果: Article

8 引用 (Scopus)

抄録

γ-glutamyl transpeptidase (γ-GTP) is a membrane-bound enzyme which is known to play a crucial role in active transport of amino acids across membrane barriers. We prepared a monoclonal antibody recognizing specifically rat γ-GTP and investigated localization of the enzyme in the rat brain by immunohistochemistry with this antibody. The antigen was localized on the ependyma, epithelia of the choroid plexus and microvessels. More precise localization of γ-GTP was examined with immuno-electron microscopy. The antigen was recognized on the microvilli and cilia of the ependymal cells, microvilli of the choroid epithelial cells and luminal membranes of the vascular endothelial cells.

元の言語English
ページ(範囲)597-601
ページ数5
ジャーナルTissue and Cell
30
発行部数6
DOI
出版物ステータスPublished - 1998 1 1
外部発表Yes

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

これを引用

Immunohistochemical study of localization of γ-glutamyl transpeptidase in the rat brain. / Ogawa, M.; Shiozawa, M.; Hiraoka, Y.; Takeuchi, Y.; Aiso, Sadakazu.

:: Tissue and Cell, 巻 30, 番号 6, 01.01.1998, p. 597-601.

研究成果: Article

Ogawa, M. ; Shiozawa, M. ; Hiraoka, Y. ; Takeuchi, Y. ; Aiso, Sadakazu. / Immunohistochemical study of localization of γ-glutamyl transpeptidase in the rat brain. :: Tissue and Cell. 1998 ; 巻 30, 番号 6. pp. 597-601.
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