In vitro culture of thymic epithelial cells from various autoimmune diseases: Its thymosin-like effect on human peripheral lymphocytes

Y. Mizuno, M. Muraoka, S. Aiso, Y. Munakata, A. Ono, M. Tsuchiya, K. Shimabukuro, M. Ito

研究成果: Article査読

7 被引用数 (Scopus)

抄録

We succeeded in the culture of the thymic epithelium obtained from patients with various autoimmune diseases aged from 20 to 65 years whose thymuses should have already been involuted with decreased thymic function. The mean percentage of active rosette-forming cells significantly increased after the incubation with thymic monolayer culture medium. These observations suggest that thymic epithelia in autoimmune diseases produce thymosin-like factor(s) in culture medium.

本文言語English
ページ(範囲)329-334
ページ数6
ジャーナルBiochemistry and Experimental Biology
14
4
出版ステータスPublished - 1978
外部発表はい

ASJC Scopus subject areas

  • Medicine(all)

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