Integration of decellularized ligament and artificial material through recellularization for periodontal reconstruction

Naoko Nakamura, Hiroki Harukaze, Ryota Ohira, Masahiro Yamada, Toshiya Fujisato, Tsuyoshi Kimura, Akio Kishida

研究成果: Conference contribution

抜粋

Dental implant treatment is a major treatment for lack of teeth. Dental implant directly binds to bone of jaw. Our teeth are normally supported by periodontal membranes which exist between teeth and mandible bone and consist of collagen fibers. The lack of the periodontal membrane is one of problems of dental implant treatment because periodontal membrane acts as many functions, such as supporting teeth, feeling, and preventing form the infection. In order to overcome this problem, we have tried preparing the unit of mandible bone, periodontal membrane and artificial tooth. In previous research, the mandible bone and periodontal membrane were prepared by decellularization method. And artificial tooth was prepared by 3-D printer and their surface was modified by calcification method. These were implanted together in rat renal capsule, and then the rat host cells infiltrated the periodontal membrane and construct the extracellular matrix between decellularized mandible bone and artificial tooth. It was suggested the collagen fibers of decellularized periodontal membrane was combined with the surface of artificial tooth. In this study, we targeted to reveal the combining of decellularized ligament and artificial material, because it is most important for periodontal reconstruction. We here developed the simple model which consists of ligament extracellular matrix sheet and artificial material plate. And we investigated the combining of collagen fibers and material surface by implanting them in vivo.

元の言語English
ホスト出版物のタイトルSociety for Biomaterials Annual Meeting and Exposition 2019
ホスト出版物のサブタイトルThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
出版者Society for Biomaterials
ページ数1
ISBN(電子版)9781510883901
出版物ステータスPublished - 2019 1 1
イベント42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
継続期間: 2019 4 32019 4 6

出版物シリーズ

名前Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
40
ISSN(印刷物)1526-7547

Conference

Conference42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
United States
Seattle
期間19/4/319/4/6

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Biotechnology
  • Biomaterials
  • Materials Chemistry

フィンガープリント Integration of decellularized ligament and artificial material through recellularization for periodontal reconstruction' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Nakamura, N., Harukaze, H., Ohira, R., Yamada, M., Fujisato, T., Kimura, T., & Kishida, A. (2019). Integration of decellularized ligament and artificial material through recellularization for periodontal reconstruction. : Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; 巻数 40). Society for Biomaterials.