Intramolecular Diels-Alder reaction of N-allyl 2-furoyl amides: Effect of steric strain and amide rotational isomerism

Medicine & Life Sciences

• Amides 71%
• Cyclization 30%
• Cycloaddition Reaction 100%
• Density Functional Theory 34%
• Isomerism 97%
• Nitrogen 19%

Chemical Compounds

• Amide 42%
• Cyclization Reaction 14%
• Density Functional Theory 12%
• Diels-Alder Intramolecular Cycloaddition 77%
• Nitrogen Atom 16%
• Strain 41%
• Substituent Effect 20%