Magnetically driven micro-movable electrode for cell coupling

Y. Yamanishi, T. Kawahara, T. Iyanagi, M. Hagiwara, Fumihito Arai

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

We developed a novel method of cell coupling on a chip by using magnetically driven microtool (MMT). It is made of nickel and is used as an electrode as well as a cell pusher. The novelty of this device is the electrode itself whose tip part is supported by a spring and is positioned by external magnetic field. We propose a new cell coupling chip which provides larger coupling force of cells by using a physical motion of MMT. The operation of the microelectrode showed that the oocyte is deformed and the donor cell is successfully coupled physically with the oocyte. The contact area between the cells was increased, and which is good for consequent fusion process. The FEM analysis on the electric field density also showed that a high concentration between the membrane of oocyte and donor cell. The proposed method is suited for cell fusion on a chip, and will contribute to high throughput cell manipulation.

本文言語English
ホスト出版物のタイトル14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
ページ905-907
ページ数3
出版ステータスPublished - 2010 12 1
イベント14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
継続期間: 2010 10 32010 10 7

出版物シリーズ

名前14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
2

Conference

Conference14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
CountryNetherlands
CityGroningen
Period10/10/310/10/7

ASJC Scopus subject areas

  • Control and Systems Engineering

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