TY - GEN
T1 - Microfluidic immunoassay for alveolar cell released interleukin-8 using a braille display for computer-controlled fluid actuation
AU - Kamotani, Y.
AU - Gu, W.
AU - Futai, N.
AU - Takayama, S.
PY - 2006
Y1 - 2006
N2 - We have developed a self-contained, connectorless, automated microfluidic immunoassay system to detect and quantify levels of Interleukin (IL)-8, an important cytokine involved in the inflammatory response. In our microfluidic system, liquid flow is controlled using the pins of a commercially available, refreshable Braille display that act as small mechanical actuators. The successful development of such a microsystem will prove beneficial in both the early diagnosis and treatment of various disease states. Integration of the microfluidic immunoassay system with cell culture can provide a novel, self-contained device to analyze the by-products of chemically stimulated cells in a controlled microenvironment.
AB - We have developed a self-contained, connectorless, automated microfluidic immunoassay system to detect and quantify levels of Interleukin (IL)-8, an important cytokine involved in the inflammatory response. In our microfluidic system, liquid flow is controlled using the pins of a commercially available, refreshable Braille display that act as small mechanical actuators. The successful development of such a microsystem will prove beneficial in both the early diagnosis and treatment of various disease states. Integration of the microfluidic immunoassay system with cell culture can provide a novel, self-contained device to analyze the by-products of chemically stimulated cells in a controlled microenvironment.
KW - Bead-based immunoassay
KW - Epithelial cell culture
KW - Microfiuidics
UR - http://www.scopus.com/inward/record.url?scp=35548993346&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=35548993346&partnerID=8YFLogxK
U2 - 10.1109/MMB.2006.251487
DO - 10.1109/MMB.2006.251487
M3 - Conference contribution
AN - SCOPUS:35548993346
SN - 1424403383
SN - 9781424403387
T3 - Proceedings of 2006 International Conference on Microtechnologies in Medicine and Biology
SP - 49
EP - 51
BT - Proceedings of 2006 International Conference on Microtechnologies in Medicine and Biology
T2 - 2006 International Conference on Microtechnologies in Medicine and Biology
Y2 - 9 May 2006 through 12 May 2006
ER -