The tissue pO2-dependent regulation of microvascular blood flow was evaluated in rabbit skeletal muscle in vivo. The rabbit tenuissimus muscle was prepared to observe the microcirculation. The capillary red blood cell velocity and perfused capillary density at various tissue pO2 levels were measured from the images of microcirculation obtained by an intravital video-microscope. Both velocity and density were significantly decreased as tissue pO2 was elevated, but the relationship between capillary flow and tissue pO2 was not a linear correlation. In addition, the critical pO2 value effected on microvascular blood flow regulation might exist in the tissue pO2 ranging between 30 to 50 ninvllg. It is suggested that the arteriolar walls might detect such a pO2 value and control capillary blood flow directly by influencing the tonus of their smooth muscle.
|ジャーナル||Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings|
|出版ステータス||Published - 2003|
|イベント||A New Beginning for Human Health: Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Cancun, Mexico|
継続期間: 2003 9月 17 → 2003 9月 21
ASJC Scopus subject areas
- コンピュータ ビジョンおよびパターン認識