Observation of subcellular nanostructure of single neurons with an illumination mode photon scanning tunneling microscope

R. Uma Maheswari, H. Tatsumi, Y. Katayama, M. Ohtsu

研究成果: Article査読

32 被引用数 (Scopus)

抄録

We report about the observation of microtubules lying underneath the cell membrane of neural process in neurons with a resolution as high as that of an electron microscope by an illumination mode photon scanning tunneling microscope. Nanoapertures used in our observations were fabricated by means of selective chemical etching and metal coating of an optical fiber. The narrowest observed tube has got an average diameter of 26 nm. Comparing this with its nominal value of 25 nm, the difference which is considered as a measure of resolution (δ) is 1 nm implying a resolution comparable to that of an electron microscope in imaging dielectric specimens. This was possible due to the presence of a boundary between the glass and the metal coating and also due to the use of an aperture of almost the same size as that of the microtubule that enhances the detection.

本文言語English
ページ(範囲)325-334
ページ数10
ジャーナルOptics Communications
120
5-6
DOI
出版ステータスPublished - 1995 11 1
外部発表はい

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 原子分子物理学および光学
  • 物理化学および理論化学
  • 電子工学および電気工学

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