抄録
In this paper, we developed and fabricated a magnetically driven microtool (MMT) and installed it on a microfluidic chip for use in the enucleation of oocytes. The fabricated tool is much smaller than a conventional mechanical micromanipulator used for cell manipulation. We succeeded in driving this MMT in two degrees of freedomin the X - and Y -directions. The MMT works on the principle of noncontact actuation by magnetic force; therefore, the microfluidic-chip part is fully disposable and inexpensive. The MMT consists of a polymer part with a controllable attitude and a rigid metal (Ni) part with good magnetic properties, which are useful for cutting oocytes. We analytically evaluated that the structure for easy attitude control of the polymer part is a four-leg-type configuration. Based on the novel and original design, the MMT and microfluidic chip were fabricated by photolithography. The MMT could generate a force of 3 mN, which is sufficient to cut an oocyte into half. We successfully demonstrated the cutting of an oocyte on a microfluidic chip by using the MMT.
本文言語 | English |
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論文番号 | 5686907 |
ページ(範囲) | 383-388 |
ページ数 | 6 |
ジャーナル | Journal of Microelectromechanical Systems |
巻 | 20 |
号 | 2 |
DOI | |
出版ステータス | Published - 2011 4月 |
外部発表 | はい |
ASJC Scopus subject areas
- 機械工学
- 電子工学および電気工学