On-chip single particle loading and dispensing

Huseyin Uvet, Lin Feng, Shigeo Ohashi, Masaya Hagiwara, Tomohiro Kawahara, Yoko Yamanishi, Fumihito Arai

研究成果: Conference contribution

9 被引用数 (Scopus)

抄録

In this paper, on-chip particle loading and dispensing modules are presented with their results for the automation of a single particle retrieving from a microfluidic channel. Our proposed microfluidic chip has several modules. Each one of them has important functions as (a) loading micro-particles singly to main microfluidic flow by the aid of magnetically driven microtools (MMT); (b) finding particle position in a microfluidic channel by micro-capacitance sensors; (c) adjusting micro-channel height locally by pneumatic pressure valve; (d) dispensing particles out from the microfluidic chip to incubation environment. Novelty of this paper is summarized as follows: (1) Multi-photoresist combination technique for the pneumatic pressure valve; (2) Automatic on-chip particle dispensing with micro-capacitance sensors. We showed feasibility of automatic dispensing of a single polystyrene bead (about 100 μm) from the chip to atmosphere. The performances of each module (hybrid structure, sensor and dispensing parts) were evaluated individually. We succeeded in determination of the movement of micro-particles (about 50-100 μm) with the velocity of over 6 mm/sec. by the micro-capacitance sensors. The advantages of the proposed system are that composed of the reusable drive system such as xy motorized stage, pumps and a disposable microfluidic chip.

本文言語English
ホスト出版物のタイトル2011 IEEE International Conference on Robotics and Automation, ICRA 2011
ページ3151-3156
ページ数6
DOI
出版ステータスPublished - 2011 12 1
イベント2011 IEEE International Conference on Robotics and Automation, ICRA 2011 - Shanghai, China
継続期間: 2011 5 92011 5 13

出版物シリーズ

名前Proceedings - IEEE International Conference on Robotics and Automation
ISSN(印刷版)1050-4729

Conference

Conference2011 IEEE International Conference on Robotics and Automation, ICRA 2011
国/地域China
CityShanghai
Period11/5/911/5/13

ASJC Scopus subject areas

  • ソフトウェア
  • 制御およびシステム工学
  • 人工知能
  • 電子工学および電気工学

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