Oxygen consumption by arteriolar wall during enhancement and inhibition of nitric oxide synthesis

M. Shibata, N. Ohura, S. Ichioka

研究成果: Conference contribution

抄録

To study the role of nitric oxide (NO) in regulating oxygen consumption by vessel walls, the oxygen consumption rate of arteriolar walls in rat cremaster muscle was measured during enhancement and inhibition of NO synthesis. The oxygen consumption rate of arteriolar walls was calculated based on the intra-and peri-vascular oxygen tension (PO2) measured by phosphorescence quenching microscopy. The inhibition of NO synthesis increased the oxygen consumption rate of the vessel walls by 42%, whereas enhancement of flow-induced NO release decreased it by 34%. These results suggest that NO plays an important role not only as a regulator of peripheral vascular tone, but also as a modulator of tissue oxygen consumption by reducing oxygen consumption by vessel walls.

本文言語English
ホスト出版物のタイトルWorld Congress on Medical Physics and Biomedical Engineering
ホスト出版物のサブタイトルImage Processing, Biosignal Processing, Modelling and Simulation, Biomechanics
出版社Springer Verlag
ページ125-128
ページ数4
4
ISBN(印刷版)9783642038815
DOI
出版ステータスPublished - 2009
イベントWorld Congress on Medical Physics and Biomedical Engineering: Image Processing, Biosignal Processing, Modelling and Simulation, Biomechanics - Munich, Germany
継続期間: 2009 9 72009 9 12

出版物シリーズ

名前IFMBE Proceedings
番号4
25
ISSN(印刷版)1680-0737

Conference

ConferenceWorld Congress on Medical Physics and Biomedical Engineering: Image Processing, Biosignal Processing, Modelling and Simulation, Biomechanics
国/地域Germany
CityMunich
Period09/9/709/9/12

ASJC Scopus subject areas

  • バイオエンジニアリング
  • 生体医工学

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