Oxygen consumption by arteriolar wall during enhancement and inhibition of nitric oxide synthesis

Masahiro Shibata, N. Ohura, S. Ichioka

研究成果: Conference contribution

抄録

To study the role of nitric oxide (NO) in regulating oxygen consumption by vessel walls, the oxygen consumption rate of arteriolar walls in rat cremaster muscle was measured during enhancement and inhibition of NO synthesis. The oxygen consumption rate of arteriolar walls was calculated based on the intra-and peri-vascular oxygen tension (PO2) measured by phosphorescence quenching microscopy. The inhibition of NO synthesis increased the oxygen consumption rate of the vessel walls by 42%, whereas enhancement of flow-induced NO release decreased it by 34%. These results suggest that NO plays an important role not only as a regulator of peripheral vascular tone, but also as a modulator of tissue oxygen consumption by reducing oxygen consumption by vessel walls.

元の言語English
ホスト出版物のタイトルIFMBE Proceedings
ページ125-128
ページ数4
25
エディション4
DOI
出版物ステータスPublished - 2009
イベントWorld Congress on Medical Physics and Biomedical Engineering: Image Processing, Biosignal Processing, Modelling and Simulation, Biomechanics - Munich
継続期間: 2009 9 72009 9 12

Other

OtherWorld Congress on Medical Physics and Biomedical Engineering: Image Processing, Biosignal Processing, Modelling and Simulation, Biomechanics
Munich
期間09/9/709/9/12

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Nitric oxide
Nitric Oxide
Oxygen
Phosphorescence
Modulators
Muscle
Rats
Quenching
Microscopic examination
Tissue

ASJC Scopus subject areas

  • Biomedical Engineering
  • Bioengineering

これを引用

Oxygen consumption by arteriolar wall during enhancement and inhibition of nitric oxide synthesis. / Shibata, Masahiro; Ohura, N.; Ichioka, S.

IFMBE Proceedings. 巻 25 4. 編 2009. p. 125-128.

研究成果: Conference contribution

Shibata, M, Ohura, N & Ichioka, S 2009, Oxygen consumption by arteriolar wall during enhancement and inhibition of nitric oxide synthesis. : IFMBE Proceedings. 4 Edn, 巻. 25, pp. 125-128, World Congress on Medical Physics and Biomedical Engineering: Image Processing, Biosignal Processing, Modelling and Simulation, Biomechanics, Munich, 09/9/7. https://doi.org/10.1007/978-3-642-03882-2-32
Shibata, Masahiro ; Ohura, N. ; Ichioka, S. / Oxygen consumption by arteriolar wall during enhancement and inhibition of nitric oxide synthesis. IFMBE Proceedings. 巻 25 4. 版 2009. pp. 125-128
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