To synthesize artificial bones, the collagen orientation is one of the key issues. It is reported that high magnetic field could be generated by superconducting magnets, are effective in controlling collagen orientation. In this paper, magnetic circuit using permanent magnets for collagen orientation is studied. As the results, a compact magnetic circuit with magnetic field strength around 3 T has been developed. By using the magnetic circuit, collagen was highly oriented, and orientation order was 0.9. Mouse osteoblast cells were seeded on the orientated collagen solution and cultured. The collagen-gel shrinkages by cells were observed. The shrinkage rates of oriented collagen are higher than that of not oriented one.
|ジャーナル||Physica Status Solidi (C) Current Topics in Solid State Physics|
|出版ステータス||Published - 2007|
|イベント||International Symposium on Advanced Magnetic Materials and Appilications, (ISAMMA 2007) - Jeju, Korea, Republic of|
継続期間: 2007 5月 28 → 2007 6月 1
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