TY - JOUR
T1 - Permanent magnets circuit for collagen orientation
AU - Shinohara, Tadashi
AU - Saito, Tomoyuki
AU - Saito, Daisuke
AU - Kotani, Makoto
AU - Aoki, Masaaki
PY - 2007
Y1 - 2007
N2 - To synthesize artificial bones, the collagen orientation is one of the key issues. It is reported that high magnetic field could be generated by superconducting magnets, are effective in controlling collagen orientation. In this paper, magnetic circuit using permanent magnets for collagen orientation is studied. As the results, a compact magnetic circuit with magnetic field strength around 3 T has been developed. By using the magnetic circuit, collagen was highly oriented, and orientation order was 0.9. Mouse osteoblast cells were seeded on the orientated collagen solution and cultured. The collagen-gel shrinkages by cells were observed. The shrinkage rates of oriented collagen are higher than that of not oriented one.
AB - To synthesize artificial bones, the collagen orientation is one of the key issues. It is reported that high magnetic field could be generated by superconducting magnets, are effective in controlling collagen orientation. In this paper, magnetic circuit using permanent magnets for collagen orientation is studied. As the results, a compact magnetic circuit with magnetic field strength around 3 T has been developed. By using the magnetic circuit, collagen was highly oriented, and orientation order was 0.9. Mouse osteoblast cells were seeded on the orientated collagen solution and cultured. The collagen-gel shrinkages by cells were observed. The shrinkage rates of oriented collagen are higher than that of not oriented one.
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U2 - 10.1002/pssc.200777290
DO - 10.1002/pssc.200777290
M3 - Conference article
AN - SCOPUS:38349117697
VL - 4
SP - 4333
EP - 4336
JO - Physica Status Solidi C: Conferences
JF - Physica Status Solidi C: Conferences
SN - 1862-6351
IS - 12
T2 - International Symposium on Advanced Magnetic Materials and Appilications, (ISAMMA 2007)
Y2 - 28 May 2007 through 1 June 2007
ER -