Photoacoustic mammography capable of simultaneously acquiring photoacoustic and ultrasound images

Yasufumi Asao, Yohei Hashizume, Takahiro Suita, Ken Ichi Nagae, Kazuhiko Fukutani, Yoshiaki Sudo, Toshikazu Matsushita, Shuichi Kobayashi, Mariko Tokiwa, Iku Yamaga, Elham Fakhrejahani, Masae Torii, Masahiro Kawashima, Masahiro Takada, Shotaro Kanao, Masako Kataoka, Tsuyoshi Shiina, Masakazu Toi

研究成果: Article査読

37 被引用数 (Scopus)

抄録

We have constructed a prototype photoacoustic mammography system (PAM-02) capable of simultaneously acquiring photoacoustic (PA) and ultrasound (US) images. Each PA, US, and fused PA/US image can be acquired over a wide area of the breast using the scanning module of a US transducer, a PA detector, and optical prisms. The resolution of the PA images exhibits improvement from 2 to 1 mm compared to images acquired using our previous prototype. The maximum scan area of PAM-02 is 90 mm along the horizontal axis and 150 mm along the vertical axis. In a phantom experiment, the available depth was at least 45 mm. A representative example of the application of the PAM-02 prototype in clinical research at Kyoto University is presented and shows S-factor images, which are considered an approximation parameter related to hemoglobin saturation of tumor-related blood vessels. We confirmed the applicability of the system for anatomical and biological research.

本文言語English
論文番号116009
ジャーナルJournal of biomedical optics
21
11
DOI
出版ステータスPublished - 2016 11月 1
外部発表はい

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 生体材料
  • 原子分子物理学および光学
  • 生体医工学

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