PLP-I: A novel prolactin-like gene in rodents

Yoshiki Hiraoka, Motoyuki Ogawa, Yukinao Sakai, Yuji Takeuchi, Naoki Komatsu, Masahide Shiozawa, Kiyoo Tanabe, Sadakazu Aiso

研究成果: Article査読

15 被引用数 (Scopus)

抄録

In this report, we describe molecular cloning and characterization of cDNAs encoding a novel rat prolactin-like protein. The rat cDNAs were isolated from the decidua and the gene was named PLP-I. cDNAs for the mouse equivalent were also cloned by the cross-hybridization technique. Pregnancy-specific expression of the rat PLP-I gene was observed in the rat placenta by Northern analysis. Location of signal peptide cleavage sites in rat and mouse pre-PLP-I proteins was predicted using a theoretical method. A molecular phylogenetic tree for the growth hormone-prolactin superfamily including the novel member, PLP-I, constructed using the neighbor-joining method, places rat/mouse PLP-I closest to rat/mouse placental lactogen I and II. Copyright (C) 1999 Elsevier Science B.V.

本文言語English
ページ(範囲)291-297
ページ数7
ジャーナルBiochimica et Biophysica Acta - Gene Structure and Expression
1447
2-3
DOI
出版ステータスPublished - 1999 10 28
外部発表はい

ASJC Scopus subject areas

  • 構造生物学
  • 生物理学
  • 生化学
  • 遺伝学

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