Poly-ε-Lysine Modified Nanocarbon Film Electrodes for LPS Detection

Dai Kato, Atsumu Oda, Mutsuo Tanaka, Seiichiro Iijima, Tomoyuki Kamata, Masami Todokoro, Yasuo Yoshimi, Osamu Niwa

研究成果: Article

4 引用 (Scopus)

抜粋

We developed an electrochemical system for detecting lipopolysaccharide (LPS) that uses an ultraflat nanocarbon film electrode modified with poly-ε-lysine with a high affinity to LPS. LPS was captured on the modified electrode, and then ferrocene labeled polymyxin B (FcPMB) was captured on the LPS adsorbed electrode via the LPS-PMB affinity interaction. The adsorbed FcPMB provided an amplified response with Fe2+ ions, and the current response was dependent on the amount of captured LPS (LOD=2.0ng/mL). This was due to the efficient accumulation of the obtained current for LPS and the very low noise made possible by the ultraflat surface.

元の言語English
ページ(範囲)618-624
ページ数7
ジャーナルElectroanalysis
26
発行部数3
DOI
出版物ステータスPublished - 2014 3 1

    フィンガープリント

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry

これを引用

Kato, D., Oda, A., Tanaka, M., Iijima, S., Kamata, T., Todokoro, M., Yoshimi, Y., & Niwa, O. (2014). Poly-ε-Lysine Modified Nanocarbon Film Electrodes for LPS Detection. Electroanalysis, 26(3), 618-624. https://doi.org/10.1002/elan.201300542