抄録
We developed an electrochemical system for detecting lipopolysaccharide (LPS) that uses an ultraflat nanocarbon film electrode modified with poly-ε-lysine with a high affinity to LPS. LPS was captured on the modified electrode, and then ferrocene labeled polymyxin B (FcPMB) was captured on the LPS adsorbed electrode via the LPS-PMB affinity interaction. The adsorbed FcPMB provided an amplified response with Fe2+ ions, and the current response was dependent on the amount of captured LPS (LOD=2.0ng/mL). This was due to the efficient accumulation of the obtained current for LPS and the very low noise made possible by the ultraflat surface.
本文言語 | English |
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ページ(範囲) | 618-624 |
ページ数 | 7 |
ジャーナル | Electroanalysis |
巻 | 26 |
号 | 3 |
DOI | |
出版ステータス | Published - 2014 3月 |
ASJC Scopus subject areas
- 分析化学
- 電気化学