Prototyping the experimental setup to quantify the tissue oxygen consumption rate and its preliminary test

Nobuo Watanabe, Masahiro Shibata, S. Sawada, K. Mizukami

研究成果: Conference contribution

抜粋

In order to establish a reliable and practical method to make a diagnosis on the viability of an amputated extremity, we propose a method to evaluate the oxygen consumption rate. To validate this concept, we prototyped an experimental system with which the oxygen transfer rate into tissue can be assessed by the rate of change of the decrease in dissolved oxygen (DO) concentration within the buffer fluid surrounding the target tissue. The purpose of this study is to examine the feasibility of our prototyped experimental system by comparison between fresh and non-fresh rat skeletal muscles. The results show that the fresher tissue transferred more oxygen to the tissue, which suggests that tissue oxygen consumption is highly related to tissue freshness and can indirectly assess the tissue viability.

元の言語English
ホスト出版物のタイトルAdvances in Experimental Medicine and Biology
出版者Springer New York LLC
ページ247-255
ページ数9
876
ISBN(印刷物)9781493930227
DOI
出版物ステータスPublished - 2016
イベント42nd Annual Meeting of International Society on Oxygen Transport to Tissue - London, United Kingdom
継続期間: 2014 6 282014 7 3

出版物シリーズ

名前Advances in Experimental Medicine and Biology
876
ISSN(印刷物)00652598
ISSN(電子版)22148019

Other

Other42nd Annual Meeting of International Society on Oxygen Transport to Tissue
United Kingdom
London
期間14/6/2814/7/3

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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  • これを引用

    Watanabe, N., Shibata, M., Sawada, S., & Mizukami, K. (2016). Prototyping the experimental setup to quantify the tissue oxygen consumption rate and its preliminary test. : Advances in Experimental Medicine and Biology (巻 876, pp. 247-255). (Advances in Experimental Medicine and Biology; 巻数 876). Springer New York LLC. https://doi.org/10.1007/978-1-4939-3023-4_31