抄録
A new and general method of iodine-mediated cyclization reactions of unsaturated carbamates, ureas and amides which gives N-cyclized products as a single regio-isomer was achieved. The present reaction proceeds in good yield through regio-control of an ambident nucleophile by LiAl(Ot-Bu)4, and the regio-control (N-attack vs O-attack) was also found to be remarkably affected by the additive employed.
本文言語 | English |
---|---|
ページ(範囲) | 615-618 |
ページ数 | 4 |
ジャーナル | Tetrahedron Letters |
巻 | 38 |
号 | 4 |
DOI | |
出版ステータス | Published - 1997 1月 27 |
外部発表 | はい |
ASJC Scopus subject areas
- 生化学
- 創薬
- 有機化学