Size-dependent filtration and trapping of microparticle in a microfluidic chip using centrifugal force and a graduated mechanical gap

Hisataka Maruyama, Shinya Sakuma, Yoko Yamanishi, Fumihito Arai

研究成果: Conference contribution

1 引用 (Scopus)

抜粋

We proposed size-dependent microparticle filtration and particle trap by centrifugal force and mechanical restriction using three-dimensional magnetically driven microtool (3D-MMT) in a microfluidic chip. Novelties of this paper are summarized as follows. (1) Filtration of particles is robust against pressure fluctuation in microchannels rather than using only hydrodynamic force because particles are separated mechanically, (2) Clogging of the microparticles could be avoided by rotation of the 3D-MMT in a mcirochamber, (3) Size-classified microparticles can be trapped along the gaps in microchannels by flow control. Microparticles having different sizes flow in spiral microchannels and filtered according to their sizes by gaps between gaps and substrate by centrifugal force. Microparticles larger than the gap cannot pass through the gap and are kept flowing in the inner microchannel. Rotation of the 3D-MMT by magnetic force from an external magnetic circuit generates swirling flow in the microchamber. Size-classified microparticles can be trapped in microchannel by closing the drain port of the target particle. Trapped particles can be measured by direct observation and treated by reagent. After the experiment, trapped particles are extracted by open the drain ports. We successfully demonstrated microparticle filtration and microparticle trap of filtered particles in the developed microfluidic chip.

元の言語English
ホスト出版物のタイトル2009 IEEE/SICE International Symposium on System Integration
ホスト出版物のサブタイトルSI International 2008 - The 2nd Symposium on System Integration
ページ7-12
ページ数6
DOI
出版物ステータスPublished - 2009
イベント2nd International Symposium on System Integration, SII 2009 - Tokyo, Japan
継続期間: 2009 11 292009 11 29

出版物シリーズ

名前2009 IEEE/SICE International Symposium on System Integration: SI International 2008 - The 2nd Symposium on System Integration

Conference

Conference2nd International Symposium on System Integration, SII 2009
Japan
Tokyo
期間09/11/2909/11/29

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computational Theory and Mathematics

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  • これを引用

    Maruyama, H., Sakuma, S., Yamanishi, Y., & Arai, F. (2009). Size-dependent filtration and trapping of microparticle in a microfluidic chip using centrifugal force and a graduated mechanical gap. : 2009 IEEE/SICE International Symposium on System Integration: SI International 2008 - The 2nd Symposium on System Integration (pp. 7-12). [5384565] (2009 IEEE/SICE International Symposium on System Integration: SI International 2008 - The 2nd Symposium on System Integration). https://doi.org/10.1109/SI.2009.5384565