Synthesis of methyl 1-O-(4-hydroxymethamphetaminyl)-α-D- glucopyranouronate

Rika Nakajima, Machiko Ono, Sadakazu Aiso, Hiroyuki Akita

研究成果: Article

13 引用 (Scopus)

抄録

For the purpose of the direct characterization of the intact conjugated form in the urine of a methamphetamine (MA) abuser, 4-hydroxymethamphetamine (4-OHMA) glucuronate, corresponding to one of the metabolites of MA, was synthesized from the commercially available methyl 4-hydroxyphenylacetate.

元の言語English
ページ(範囲)684-687
ページ数4
ジャーナルChemical and Pharmaceutical Bulletin
53
発行部数6
DOI
出版物ステータスPublished - 2005 6 1
外部発表Yes

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Methamphetamine
Glucuronic Acid
Metabolites
pholedrine
4-hydroxyphenylacetate

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Chemistry(all)
  • Pharmacology

これを引用

Synthesis of methyl 1-O-(4-hydroxymethamphetaminyl)-α-D- glucopyranouronate. / Nakajima, Rika; Ono, Machiko; Aiso, Sadakazu; Akita, Hiroyuki.

:: Chemical and Pharmaceutical Bulletin, 巻 53, 番号 6, 01.06.2005, p. 684-687.

研究成果: Article

Nakajima, Rika ; Ono, Machiko ; Aiso, Sadakazu ; Akita, Hiroyuki. / Synthesis of methyl 1-O-(4-hydroxymethamphetaminyl)-α-D- glucopyranouronate. :: Chemical and Pharmaceutical Bulletin. 2005 ; 巻 53, 番号 6. pp. 684-687.
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