抄録
N-Substituted anilide derivatives bearing a large substitutent such as a tert-Bu group at the ortho-position have atropisomerism due to the high rotation barrier of the N-Ar bond and resist racemization. We have succeeded in the synthesis of such atropisomeric N-Ar amides, imides and lactams with high optically purity and definite absolute configuration, and the development of various asymmetric reactions using them. Furthermore, catalytic asymmetric reaction with such atropisomeric anilide as a chiral ligand is also described.
本文言語 | English |
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ページ(範囲) | 680-688 |
ページ数 | 9 |
ジャーナル | Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry |
巻 | 59 |
号 | 7 |
DOI | |
出版ステータス | Published - 2001 |
外部発表 | はい |
ASJC Scopus subject areas
- 有機化学