抄録
A series of novel thermosensitive macroporous poly (ethylene glycol) (PEG)-co-poly(N-isopropylacrylamide) (PNIPAAm)-co-poly (e-caprolactone) (PCL) hydrogels were synthesized via in situ free radical polymerization. Poly(ethylene glycol diacrylate) (PEGDAc) and poly(e-caprolactone diacrylate) (PCLDAc) were prepared as macrocrosslinkers. All compounds were investigated by Nuclear Magnetic Resonance (NMR) and Fourier transform-infrared spectroscopy (FT-IR). Differential Scanning Calorimetry (DSC) results showed the lower critical solution temperatures (LCSTs) of the gels were at around 31°C. The macroporous gels not only had considerable swelling ratios, but also exhibited rapid swelling kinetics and response sensitivity. Above mentioned hydrogels showed a remarkable oscillatory swelling-deswelling transition, making them have potential application in long-term drug delivery.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 223-230 |
| ページ数 | 8 |
| ジャーナル | Polymer Engineering and Science |
| 巻 | 55 |
| 号 | 1 |
| DOI | |
| 出版ステータス | Published - 2015 1 1 |
| 外部発表 | はい |
ASJC Scopus subject areas
- Chemistry(all)
- Polymers and Plastics
- Materials Chemistry