The conformational and binding properties of mono-6-deoxy-6[4-(1-ethyl-4-pyridinio)-1-pyridinio]-β-cyclodextrin (1) in complex formation with some guest compounds were examined by induced circular dichroism (ICD) spectra in aqueous solution. Compound 1 showed much stronger binding ability for some guest compounds (1: 1 complexes), compared with β-cyclodextrin (β-CDx) and a positively charged β-CDx [C-6-mono-pyridino-β-CDx (2)]. Marked conformational changes of 1 (the spatial position of the ethyl viologen (C2V2+) group relative to the cavity in 1) were observed upon complex formation with some guests like 1-adamantanecarboxylic acid (ACA) and sodium cholate (SC).
|ジャーナル||Journal of Inclusion Phenomena and Molecular Recognition in Chemistry|
|出版ステータス||Published - 1991 6 1|
ASJC Scopus subject areas
- 化学 (全般)