Three-dimensional elemental mapping of hollow Fe 2O 3@SiO 2 mesoporous spheres using scanning confocal electron microscopy

Peng Wang, Ayako Hashimoto, Masaki Takeguchi, Kazutaka Mitsuishi, Masayuki Shimojo, Yufang Zhu, Mitsuhiro Okuda, Angus I. Kirkland, Peter D. Nellist

研究成果: Article

9 引用 (Scopus)

抄録

Energy filtered scanning confocal electron microscopy (EFSCEM) in an aberration-corrected transmission electron microscope offers an approach for three-dimensional imaging and chemical analysis of nanoscale materials related to the well-established technique of confocal scanning optical microscopy. Here, we apply EFSCEM to the compositional analysis of the core structure in candidate structures for targeted drug delivery. Element-specific optical sectioning along the specimen depth direction demonstrates the presence of additional Si in a nominal Fe 2O 3 core. The presence of Si in the core is consistent with a specific formation mechanism for the hollow structure of the core.

元の言語English
記事番号213117
ジャーナルApplied Physics Letters
100
発行部数21
DOI
出版物ステータスPublished - 2012 5 21

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hollow
scanning electron microscopy
chemical analysis
aberration
delivery
drugs
electron microscopes
microscopy
scanning
energy

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

これを引用

Three-dimensional elemental mapping of hollow Fe 2O 3@SiO 2 mesoporous spheres using scanning confocal electron microscopy. / Wang, Peng; Hashimoto, Ayako; Takeguchi, Masaki; Mitsuishi, Kazutaka; Shimojo, Masayuki; Zhu, Yufang; Okuda, Mitsuhiro; Kirkland, Angus I.; Nellist, Peter D.

:: Applied Physics Letters, 巻 100, 番号 21, 213117, 21.05.2012.

研究成果: Article

Wang, P, Hashimoto, A, Takeguchi, M, Mitsuishi, K, Shimojo, M, Zhu, Y, Okuda, M, Kirkland, AI & Nellist, PD 2012, 'Three-dimensional elemental mapping of hollow Fe 2O 3@SiO 2 mesoporous spheres using scanning confocal electron microscopy', Applied Physics Letters, 巻. 100, 番号 21, 213117. https://doi.org/10.1063/1.4714889
Wang, Peng ; Hashimoto, Ayako ; Takeguchi, Masaki ; Mitsuishi, Kazutaka ; Shimojo, Masayuki ; Zhu, Yufang ; Okuda, Mitsuhiro ; Kirkland, Angus I. ; Nellist, Peter D. / Three-dimensional elemental mapping of hollow Fe 2O 3@SiO 2 mesoporous spheres using scanning confocal electron microscopy. :: Applied Physics Letters. 2012 ; 巻 100, 番号 21.
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