抄録
Energy filtered scanning confocal electron microscopy (EFSCEM) in an aberration-corrected transmission electron microscope offers an approach for three-dimensional imaging and chemical analysis of nanoscale materials related to the well-established technique of confocal scanning optical microscopy. Here, we apply EFSCEM to the compositional analysis of the core structure in candidate structures for targeted drug delivery. Element-specific optical sectioning along the specimen depth direction demonstrates the presence of additional Si in a nominal Fe 2O 3 core. The presence of Si in the core is consistent with a specific formation mechanism for the hollow structure of the core.
本文言語 | English |
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論文番号 | 213117 |
ジャーナル | Applied Physics Letters |
巻 | 100 |
号 | 21 |
DOI | |
出版ステータス | Published - 2012 5 21 |
ASJC Scopus subject areas
- Physics and Astronomy (miscellaneous)