抄録
Energy filtered scanning confocal electron microscopy (EFSCEM) in an aberration-corrected transmission electron microscope offers an approach for three-dimensional imaging and chemical analysis of nanoscale materials related to the well-established technique of confocal scanning optical microscopy. Here, we apply EFSCEM to the compositional analysis of the core structure in candidate structures for targeted drug delivery. Element-specific optical sectioning along the specimen depth direction demonstrates the presence of additional Si in a nominal Fe 2O 3 core. The presence of Si in the core is consistent with a specific formation mechanism for the hollow structure of the core.
| 元の言語 | English |
|---|---|
| 記事番号 | 213117 |
| ジャーナル | Applied Physics Letters |
| 巻 | 100 |
| 発行部数 | 21 |
| DOI | |
| 出版物ステータス | Published - 2012 5 21 |
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ASJC Scopus subject areas
- Physics and Astronomy (miscellaneous)
これを引用
Three-dimensional elemental mapping of hollow Fe 2O 3@SiO 2 mesoporous spheres using scanning confocal electron microscopy. / Wang, Peng; Hashimoto, Ayako; Takeguchi, Masaki; Mitsuishi, Kazutaka; Shimojo, Masayuki; Zhu, Yufang; Okuda, Mitsuhiro; Kirkland, Angus I.; Nellist, Peter D.
：: Applied Physics Letters, 巻 100, 番号 21, 213117, 21.05.2012.研究成果: Article
}
TY - JOUR
T1 - Three-dimensional elemental mapping of hollow Fe 2O 3@SiO 2 mesoporous spheres using scanning confocal electron microscopy
AU - Wang, Peng
AU - Hashimoto, Ayako
AU - Takeguchi, Masaki
AU - Mitsuishi, Kazutaka
AU - Shimojo, Masayuki
AU - Zhu, Yufang
AU - Okuda, Mitsuhiro
AU - Kirkland, Angus I.
AU - Nellist, Peter D.
PY - 2012/5/21
Y1 - 2012/5/21
N2 - Energy filtered scanning confocal electron microscopy (EFSCEM) in an aberration-corrected transmission electron microscope offers an approach for three-dimensional imaging and chemical analysis of nanoscale materials related to the well-established technique of confocal scanning optical microscopy. Here, we apply EFSCEM to the compositional analysis of the core structure in candidate structures for targeted drug delivery. Element-specific optical sectioning along the specimen depth direction demonstrates the presence of additional Si in a nominal Fe 2O 3 core. The presence of Si in the core is consistent with a specific formation mechanism for the hollow structure of the core.
AB - Energy filtered scanning confocal electron microscopy (EFSCEM) in an aberration-corrected transmission electron microscope offers an approach for three-dimensional imaging and chemical analysis of nanoscale materials related to the well-established technique of confocal scanning optical microscopy. Here, we apply EFSCEM to the compositional analysis of the core structure in candidate structures for targeted drug delivery. Element-specific optical sectioning along the specimen depth direction demonstrates the presence of additional Si in a nominal Fe 2O 3 core. The presence of Si in the core is consistent with a specific formation mechanism for the hollow structure of the core.
UR - http://www.scopus.com/inward/record.url?scp=84861815449&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861815449&partnerID=8YFLogxK
U2 - 10.1063/1.4714889
DO - 10.1063/1.4714889
M3 - Article
AN - SCOPUS:84861815449
VL - 100
JO - Applied Physics Letters
JF - Applied Physics Letters
SN - 0003-6951
IS - 21
M1 - 213117
ER -