Validity of ultrasound muscle thickness measurements for predicting leg skeletal muscle mass in healthy Japanese middle-aged and older individuals

Yohei Takai, Megumi Ohta, Ryota Akagi, Emika Kato, Taku Wakahara, Yasuo Kawakami, Tetsuo Fukunaga, Hiroaki Kanehisa

研究成果: Article

21 引用 (Scopus)

抄録

Background: The skeletal muscle mass of the lower limb plays a role in its mobility during daily life. From the perspective of physical resources, leg muscle mass dominantly decreases after the end of the fifth decade. Therefore, an accurate estimate of the muscle mass is important for the middle-aged and older population. The present study aimed to clarify the validity of ultrasound muscle thickness (MT) measurements for predicting leg skeletal muscle mass (SM) in the healthy Japanese middle-aged and older population.Findings: MTs at four sites of the lower limb and the bone-free lean tissue mass (LTM) of the right leg were determined using brightness-mode ultrasonography and dual-energy X-ray absorptiometry (DXA), respectively, in 44 women and 33 men, 52- to 78-years old. LTM was used as a representative variable of leg skeletal muscle mass. In the model-development group (30 women and 22 men), regression analysis produced an equation with R2 and standard error of the estimate (SEE) of 0.958 and 0.3 kg, respectively: LTM (kg) = 0.01464 × (MTSUM×L) (cm2) - 2.767, where MTSUM is the sum of the product of MTs at four sites, and L is length of segment where MT is determined. The estimated LTM (7.0 ± 1.7 kg) did not significantly differ from the measured LTM (7.0 ± 1.7 kg), without a significant systematic error on a Bland-Altman plot. The application of this equation for the cross-validation group (14 women and 11 men) did not yield a significant difference between the measured (7.2 ± 1.6 kg) or estimated (7.2 ± 1.6 kg) LTM and systematic error.Conclusion: The developed prediction equation may be useful for estimating the lean tissue mass of the lower extremity for the healthy Japanese middle-aged and older population.

元の言語English
記事番号12
ジャーナルJournal of Physiological Anthropology
32
発行部数1
DOI
出版物ステータスPublished - 2013 9 25

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Thickness measurement
Muscle
Ultrasonics
Tissue
development model
Systematic errors
regression analysis
Group
energy
Ultrasonography
resources
Regression analysis
Luminance
Bone
X rays

ASJC Scopus subject areas

  • Physiology
  • Orthopedics and Sports Medicine
  • Physiology (medical)
  • Public Health, Environmental and Occupational Health
  • Human Factors and Ergonomics
  • Anthropology

これを引用

Validity of ultrasound muscle thickness measurements for predicting leg skeletal muscle mass in healthy Japanese middle-aged and older individuals. / Takai, Yohei; Ohta, Megumi; Akagi, Ryota; Kato, Emika; Wakahara, Taku; Kawakami, Yasuo; Fukunaga, Tetsuo; Kanehisa, Hiroaki.

:: Journal of Physiological Anthropology, 巻 32, 番号 1, 12, 25.09.2013.

研究成果: Article

Takai, Yohei ; Ohta, Megumi ; Akagi, Ryota ; Kato, Emika ; Wakahara, Taku ; Kawakami, Yasuo ; Fukunaga, Tetsuo ; Kanehisa, Hiroaki. / Validity of ultrasound muscle thickness measurements for predicting leg skeletal muscle mass in healthy Japanese middle-aged and older individuals. :: Journal of Physiological Anthropology. 2013 ; 巻 32, 番号 1.
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AU - Takai, Yohei

AU - Ohta, Megumi

AU - Akagi, Ryota

AU - Kato, Emika

AU - Wakahara, Taku

AU - Kawakami, Yasuo

AU - Fukunaga, Tetsuo

AU - Kanehisa, Hiroaki

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N2 - Background: The skeletal muscle mass of the lower limb plays a role in its mobility during daily life. From the perspective of physical resources, leg muscle mass dominantly decreases after the end of the fifth decade. Therefore, an accurate estimate of the muscle mass is important for the middle-aged and older population. The present study aimed to clarify the validity of ultrasound muscle thickness (MT) measurements for predicting leg skeletal muscle mass (SM) in the healthy Japanese middle-aged and older population.Findings: MTs at four sites of the lower limb and the bone-free lean tissue mass (LTM) of the right leg were determined using brightness-mode ultrasonography and dual-energy X-ray absorptiometry (DXA), respectively, in 44 women and 33 men, 52- to 78-years old. LTM was used as a representative variable of leg skeletal muscle mass. In the model-development group (30 women and 22 men), regression analysis produced an equation with R2 and standard error of the estimate (SEE) of 0.958 and 0.3 kg, respectively: LTM (kg) = 0.01464 × (MTSUM×L) (cm2) - 2.767, where MTSUM is the sum of the product of MTs at four sites, and L is length of segment where MT is determined. The estimated LTM (7.0 ± 1.7 kg) did not significantly differ from the measured LTM (7.0 ± 1.7 kg), without a significant systematic error on a Bland-Altman plot. The application of this equation for the cross-validation group (14 women and 11 men) did not yield a significant difference between the measured (7.2 ± 1.6 kg) or estimated (7.2 ± 1.6 kg) LTM and systematic error.Conclusion: The developed prediction equation may be useful for estimating the lean tissue mass of the lower extremity for the healthy Japanese middle-aged and older population.

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KW - Cross-validation

KW - Dual-energy X-ray absorptiometry

KW - Multiple regression analysis

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