Vascular remodeling processes in an integrated microfluidic device

Nobuyuki Futai, Takanori Sano, Masahiro Sumita, Atsushi Takano, Ryuji Yokokawa, Takashi Miura

研究成果: Conference contribution

抄録

We have succeeded in maintaining self-organized microvascular networks on-chip for over a month in a portable (71×26×28 mm) microfluidic co-culture system of endothelial cells and fibroblasts. We observed the long-term changes of microvascular networks in a microchannel. Perfusion through lumens may accelerate the remodeling processes. HUVECs formed stable lumens by around 100th day of cultivation, and the lumens could be maintained for at least 132 days.

本文言語English
ホスト出版物のタイトル21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
出版社Chemical and Biological Microsystems Society
ページ1080-1081
ページ数2
ISBN(電子版)9780692941836
出版ステータスPublished - 2020
イベント21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
継続期間: 2017 10 222017 10 26

出版物シリーズ

名前21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
国/地域United States
CitySavannah
Period17/10/2217/10/26

ASJC Scopus subject areas

  • 化学工学(その他)
  • バイオエンジニアリング

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